1974/03/09 by P C Elwood, Alexandra Cochrane, M L Burr +5 · 4 citations
Medicine · #Antiplatelet Therapy and Cardiovascular Diseases #Acute Myocardial Infarction Research #Lipoproteins and Cardiovascular Health
paper · pdf · doi:10.1136/bmj.1.5905.436
openalex publication_date 1974/03/09 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/07
The results of a randomized controlled trial of a single daily dose of acetyl salicylic acid (aspirin) in the prevention of reinfarction in 1,239 men who had had a recent myocardial infarct were statistically inconclusive. Nevertheless, they showed a reduction in total mortality of 12% at six months and 25% at twelve months after admission to the trial. Further trials are urgently required to establish whether or not this effect is real.