2017/10/16 by Koki Sano, Yasuhiro Ishida, Takuzo Aida · 1 citation
Biochemistry, Genetics and Molecular Biology · Materials Science · Engineering · #Hydrogels: synthesis, properties, applications #Supramolecular Self-Assembly in Materials #3D Printing in Biomedical Research
paper · doi:10.1002/anie.201708196
openalex publication_date 2017/10/16 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27
Owing to their water-rich structures, which are similar to those of biological tissues, hydrogels have long been regarded as promising scaffolds for artificial tissues and organs. However, in terms of the structural anisotropy, most synthetic hydrogels are substantially different from biological systems. Synthetic hydrogels are usually composed of randomly oriented three-dimensional polymer networks whereas biological systems adopt anisotropic structures with hierarchically integrated building units. Such anisotropic structures often play essential roles in biological systems to exhibit particular functions. In this context, anisotropic hydrogels provide an entry point for exploring biomimetic applications of hydrogels. Reflecting these aspects, an increasing number of studies on anisotropic hydrogels have been reported recently. This Minireview highlights the use and perspectives of these anisotropic hydrogels, particularly focusing on their preparation, structures, and applications.