2001/07/01 by Boaz Weisz, Eyal Schiff, Michael Lishner · 2 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Cancer Risks and Factors #Endometrial and Cervical Cancer Treatments #Breast Cancer Treatment Studies
paper · doi:10.1093/humupd/7.4.384
openalex publication_date 2001/07/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/22
Cancer is the second leading cause of death in women during their reproductive years, and complicates approximately 0.1% of all pregnancies. When cancer occurs during gestation it poses immense pressure on the pregnant patient, her relatives and her physicians. As cancer is diagnosed during gestation, it raises conflicts between optimal maternal therapy and fetal well-being. In this review, the available data are analysed regarding the impact of pregnancy on the course of the disease, and the effects of the malignant process and its treatment on both the mother and her fetus. Here, attention is focused on the most common malignancies associated with pregnancy; cervical and breast cancer, malignant melanoma and lymphoma. In addition, attention is focused on the available data regarding the impact of cytotoxic and radiation treatments on the mother and fetus.