2001/06/26 by W. I. McDonald, Alistair Compston, Gilles Edan +13 · 41 citations
Medicine · Engineering · #Multiple Sclerosis Research Studies #Peripheral Neuropathies and Disorders #Ultrasound and Hyperthermia Applications
paper · doi:10.1002/ana.1032
openalex publication_date 2001/06/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/02
The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of dissemination of lesions in both time and space. Magnetic resonance imaging is integrated with dinical and other paraclinical diagnostic methods. The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including "monosymptomatic" disease suggestive of MS, disease with a typical relapsing-remitting course, and disease with insidious progression, without clear attacks and remissions. Previously used terms such as "clinically definite" and "probable MS" are no longer recommended. The outcome of a diagnostic evaluation is either MS, "possible MS" (for those at risk for MS, but for whom diagnostic evaluation is equivocal), or "not MS."