2018/08/26 by Edel Pérez‐López, Matthew Waldner, Md Musharaf Hossain +4 · 2 citations
Agricultural and Biological Sciences · #Plant Disease Resistance and Genetics #Plant Virus Research Studies #Plant Pathogens and Resistance
paper · pdf · doi:10.1080/21505594.2018.1504560
openalex publication_date 2018/08/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/29
Clubroot is an economically important disease affecting Brassica plants worldwide. Plasmodiophora brassicae is the protist pathogen associated with the disease, and its soil-borne obligate parasitic nature has impeded studies related to its biology and the mechanisms involved in its infection of the plant host. The identification of effector proteins is key to understanding how the pathogen manipulates the plant's immune response and the genes involved in resistance. After more than 140 years studying clubroot and P. brassicae, very little is known about the effectors playing key roles in the infection process and subsequent disease progression. Here we analyze the information available for identified effectors and suggest several features of effector genes that can be used in the search for others. Based on the information presented in this review, we propose a comprehensive bioinformatics pipeline for effector identification and provide a list of the bioinformatics tools available for such.