PROCHECK: a program to check the stereochemical quality of protein structures
1993/04/01 by R. A. Laskowski, Roman A. Laskowski, Malcolm W. MacArthur +4 · 24,733 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Materials Science · #Biochemistry #Business #Chemistry #Computer science #Enzyme Structure and Function #Geography #Listing (finance) #Microbial Metabolic Engineering and Bioproduction #Physics #Protein Structure and Dynamics #Quality (philosophy) #Residue (chemistry) #Suite
paper · doi:10.1107/s0021889892009944
published in Journal of Applied Crystallography 26(2), 283-291 (Wiley)
openalex publication_date 1993/04/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
Abstract
The PROCHECK suite of programs provides a detailed check on the stereochemistry of a protein structure. Its outputs comprise a number of plots in PostScript format and a comprehensive residue-by-residue listing. These give an assessment of the overall quality of the structure as compared with well refined structures of the same resolution and also highlight regions that may need further investigation. The PROCHECK programs are useful for assessing the quality not only of protein structures in the process of being solved but also of existing structures and of those being modelled on known structures.
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