Inattention and Hyperactivity-Impulsivity: Psychobiological and Evolutionary Underpinnings of ADHD

2007/03/01 by Dan J. Stein, Jin Fan, John Fossella +1 · 1 citation
Medicine · Neuroscience · #Attention Deficit Hyperactivity Disorder #Functional Brain Connectivity Studies #Neural and Behavioral Psychology Studies

paper · doi:10.1017/s1092852900020903

openalex publication_date 2007/03/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/06/11

Abstract

Attention-deficit/hyperactivity disorder is a prevalent and disabling disorder that is characterized by inattention and/or hyperactivity-impulsivity, impairment in executive functions, structural and functional abnormalities in frontal-striatal circuitry, associations with particular catecholamine gene variants, and responsiveness to dopaminergic and noradrenergic agents. There is a growing integration of findings from basic and clinical studies, of data from different methods (eg, genetics and imaging), and of empirical data with hypotheses drawn from evolutionary thinking. Here we briefly summarize work on the cognitive-affective neuroscience of attention-deficit/hyperactivity disorder.

Citations

• Behavioral inhibition, sustained attention, and executive functions: Constructing a unifying theory of ADHD.
• Is there evidence for neural compensation in attention deficit hyperactivity disorder? A review of the functional neuroimaging literature
• Validity of the Executive Function Theory of Attention-Deficit/Hyperactivity Disorder: A Meta-Analytic Review
• A 14-Month Randomized Clinical Trial of Treatment Strategies for Attention-Deficit/Hyperactivity Disorder

Cited by

• Disruptive mood dysregulation disorder [wikipedia]