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Ultrasound-assisted one pot synthesis of polysubstituted meta-terphenyls using ring transformation strategy

2019/03/26 by Samata E. Shetgaonkar, Fateh V. Singh · 1 citation
Chemistry · #Synthesis of heterocyclic compounds #Organic and Inorganic Chemical Reactions #Multicomponent Synthesis of Heterocycles

paper · doi:10.1080/00397911.2019.1591454

openalex publication_date 2019/03/26 · openalex created_date 2025/10/10 · openalex updated_date 2025/11/06

Abstract

An ultrasound-assisted rapid synthesis of meta-terphenyls 9 by the carbanion-induced ring transformation reaction of 6-aryl-5-methyl-2H-pyran-2-ones 7 with functionalized ketones 8 under basic conditions at room temperature has been delineated. The present method gives an easy access to functionally crowded m-terphenyls 9 with notable features including mild reaction condition, remarkable functional groups tolerance, shorter reaction time and high product yields.

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