Agomelatine but not melatonin improves fatigue perception: A longitudinal proof-of-concept study

2014/02/24 by M. Pardini, Matteo Pardini, Christian Cordano +17 · 1 voice · 2 citations
Medicine · Neuroscience · #Fibromyalgia and Chronic Fatigue Syndrome Research #Circadian rhythm and melatonin #Olfactory and Sensory Function Studies

paper · doi:10.1016/j.euroneuro.2014.02.010

Citations

• The Fatigue Severity Scale
• The Hospital Anxiety and Depression Scale

Cited by

• Effect of Melatonin Plus Zinc Supplementation on Fatigue Perception in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. [europepmc]
• Examination of the impact of curiosity and fatigue on brain condition. [europepmc]

Discussions

• Die Aufnahme von Agomelatin in die Off-Label-Liste basiert laut BfArM letztlich auf einer einzigen Studie von 2014 mit n=62 Fukuda-CFS. Also keine wirklich solide Grundlage. Und die klinische Evidenz [bsky, 20 points, 5 comments]