2014/01/01 by Jennifer S. Brodbelt · 2 citations
Chemistry · Engineering · #Mass Spectrometry Techniques and Applications #Analytical Chemistry and Chromatography #Ion-surface interactions and analysis
paper · doi:10.1039/c3cs60444f
openalex publication_date 2014/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
Photodissociation mass spectrometry combines the ability to activate and fragment ions using photons with the sensitive detection of the resulting product ions by mass spectrometry. This combination affords a versatile tool for characterization of biological molecules. The scope and breadth of photodissociation mass spectrometry have increased substantially over the past decade as new research groups have entered the field and developed a number of innovative applications that illustrate the ability of photodissociation to produce rich fragmentation patterns, to cleave bonds selectively, and to target specific molecules based on incorporation of chromophores. This review focuses on many of the key developments in photodissociation mass spectrometry over the past decade with a particular emphasis on its applications to biological molecules.