Fine-Scale Mapping of Disease Loci via Shattered Coalescent Modeling of Genealogies

2002/03/01 by Andrew P. Morris, A.P. Morris, John C. Whittaker +3 · 2 citations
Biochemistry, Genetics and Molecular Biology · Mathematics · #Allele #Bayesian probability #Biology #Coalescent theory #Computational biology #Evolutionary biology #Gene #Genetic Associations and Epidemiology #Genetics #Genomic variations and chromosomal abnormalities #Genomics and Rare Diseases #Haplotype #Linkage disequilibrium #Locus (genetics) #Markov chain #Markov chain Monte Carlo #Mathematics #Phylogenetics #Statistics

paper · pdf · doi:10.1086/339271

crossref issued 2002/03/01 · crossref published 2002/03/01 · crossref published-print 2002/03/01 · openalex publication_date 2002/03/01 · crossref created 2002/09/30 · crossref deposited 2021/05/28 · openalex created_date 2025/10/10 · crossref indexed 2026/02/26 · openalex updated_date 2026/07/25

Citations

• The coalescent
• Genetic and Geographical Variability in Cystic Fibrosis: Evolutionary Considerations
• Quasi-likelihood functions, generalized linear models, and the Gauss—Newton method
• Equation of State Calculations by Fast Computing Machines
• Initial sequencing and analysis of the human genome

Cited by

• Evaluating candidate agents of selective pressure for cystic fibrosis
• Coalescent theory [wikipedia]