2008/04/09 by Oded Farago · 2 citations
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Force Microscopy Techniques and Applications #Lipid Membrane Structure and Behavior #Spectroscopy and Quantum Chemical Studies #cond-mat.soft #cond-mat.stat-mech
paper · pdf · doi:10.1063/1.2918736
published as J. Chem. Phys. 128, 184105 (2008) · Accepted for publication in J. Chem. Phys
arxiv created 2008/04/09 · openalex publication_date 2008/05/13 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
Solvent-free coarse grained models represent one of the most promising approaches for molecular simulations of mesoscopically large membranes. In these models, the size of the simulated membrane is limited by the slow relaxation time of the longest bending mode. Here, we present a Monte Carlo algorithm with update moves in which all the lipids are simultaneously displaced. These collective moves result in fast excitation and relaxation of the long wavelength thermal fluctuations. We apply the method to simulations of a bilayer membrane with linear size of approximately 50 nm and show reduction in the relaxation time by two orders of magnitudes when compared to conventional Monte Carlo.