2007/11/30 by Sheng-Jun Wang, Xin-Jian Xu, Xin‐Jian Xu +4 · 15 citations
Biochemistry, Genetics and Molecular Biology · Neuroscience · Physics and Astronomy · #Biology #Channel (broadcasting) #Computer science #Excitatory postsynaptic potential #Inhibitory postsynaptic potential #Neural dynamics and brain function #Neuron #Neuroscience #Photoreceptor and optogenetics research #Spike (software development) #Synchronization (alternating current) #Telecommunications #cond-mat.dis-nn #q-bio.NC #stochastic dynamics and bifurcation
paper · pdf · doi:10.1103/physreve.78.061906
published in Physical Review E 78(6), 061906 (American Physical Society) · 8 pages, 8 figures
arxiv created 2008/11/17 · openalex publication_date 2008/12/03 · arxiv updated 2009/12/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/05
We investigate the influence of efficacy of synaptic interaction on firing synchronization in excitatory neuronal networks. We find spike death phenomena: namely, the state of neurons transits from the limit cycle to a fixed point or transient state. The phenomena occur under the perturbation of an excitatory synaptic interaction, which has a high efficacy. We show that the decrease of synaptic current results in spike death through depressing the feedback of the sodium ionic current. In the networks with the spike death property the degree of synchronization is lower and insensitive to the heterogeneity of neurons. The mechanism of the influence is that the transition of the neuron state disrupts the adjustment of the rhythm of the neurons oscillation and prevents a further increase of the firing synchronization.