2002/01/27 by Ulrich H. E. Hansmann, Luc T. Wille, U. H. E. Hansmann +1 · 3 citations
Biochemistry, Genetics and Molecular Biology · Computer Science · Physics and Astronomy · #Algorithms and Data Compression #Genomics and Chromatin Dynamics #Metaheuristic Optimization Algorithms Research #cond-mat.soft #physics.bio-ph #physics.comp-ph
paper · pdf · doi:10.1103/physrevlett.88.068105
published as Phys. Rev. Lett. 88 (2002) 068105 · to appear in Phys. Rev. Lett. (2002)
arxiv created 2002/01/27 · openalex publication_date 2002/01/28 · arxiv updated 2009/11/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
We introduce a novel heuristic global optimization method, energy landscape paving (ELP), which combines core ideas from energy surface deformation and tabu search. In appropriate limits, ELP reduces to existing techniques. The approach is very general and flexible and is illustrated here on two protein folding problems. For these examples, the technique gives faster convergence to the global minimum than previous approaches.