2001/03/05 by Erik Aurell, E. Aurell, Kim Sneppen +1 · 1 citation
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Evolution and Genetic Dynamics #Gene Regulatory Network Analysis #Origins and Evolution of Life #cond-mat.soft #q-bio
paper · pdf · doi:10.1103/physrevlett.88.048101
6 pages, 3 figures, in REVTeX
arxiv created 2001/03/05 · openalex publication_date 2002/01/01 · arxiv updated 2009/11/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28
We develop a framework to discuss the stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the lambda prophage. The formalism defines a quantitative measure of robustness of inherited states.