1999/08/31 by Elizabeth M. Cherry, Henry S. Greenside, Craig S. Henriquez · 1 citation
Physics and Astronomy · #physics.comp-ph
paper · pdf · doi:10.1103/physrevlett.84.1343
4 pages (LaTeX), 3 color PostScript figure files, submitted to PRL; Changed content of one paragraph; Correcting corrupt fig2a
arxiv created 1999/08/31 · arxiv updated 2009/12/01
For plane-wave and many-spiral states of the experimentally based Luo-Rudy 1 model of heart tissue in large (8 cm square) domains, we show that an explicit space-time-adaptive time-integration algorithm can achieve an order of magnitude reduction in computational effort and memory - but without a reduction in accuracy - when compared to an algorithm using a uniform space-time mesh at the finest resolution. Our results indicate that such an explicit algorithm can be extended straightforwardly to simulate quantitatively large-scale three-dimensional electrical dynamics over the whole human heart.