2007/05/18 by Minoru Nakao, Antti Lavikainen, Tetsuya Yanagida +2 · 27 citations
Immunology and Microbiology · Medicine · #Amoebic Infections and Treatments #Biology #Cestoda #Computer science #Congenital Anomalies and Fetal Surgery #Echinococcosis #Echinococcus #Echinococcus granulosus #Echinococcus multilocularis #Evolutionary biology #Genetics #Helminths #Metacestode #Parasitic Infections and Diagnostics #Parasitic infections in humans and animals #Phylogenetic tree #Phylogenetics #Systematics #Taxonomy (biology) #Zoology
paper · doi:10.1016/j.ijpara.2013.06.002
openalex publication_date 2007/05/18 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
Echinococcosis is a serious helminthic zoonosis in humans, livestock and wildlife. The pathogenic organisms are members of the genus Echinococcus (Cestoda: Taeniidae). Life cycles of Echinococcus spp. are consistently dependent on predator-prey association between two obligate mammalian hosts. Carnivores (canids and felids) serve as definitive hosts for adult tapeworms and their herbivore prey (ungulates, rodents and lagomorphs) as intermediate hosts for metacestode larvae. Humans are involved as an accidental host for metacestode infections. The metacestodes develop in various internal organs, particularly in liver and lungs. Each metacestode of Echinococcus spp. has an organotropism and a characteristic form known as an unilocular (cystic), alveolar or polycystic hydatid. Recent molecular phylogenetic studies have demonstrated that the type species, Echinococcus granulosus, causing cystic echinococcosis is a cryptic species complex. Therefore, the orthodox taxonomy of Echinococcus established from morphological criteria has been revised from the standpoint of phylogenetic systematics. Nine valid species including newly resurrected taxa are recognised as a result of the revision. This review summarises the recent advances in the phylogenetic systematics of Echinococcus, together with the historical backgrounds and molecular epidemiological aspects of each species. A new phylogenetic tree inferred from the mitochondrial genomes of all valid Echinococcus spp. is also presented. The taxonomic nomenclature for Echinococcus oligarthrus is shown to be incorrect and this name should be replaced with Echinococcus oligarthra.