De novo discovery of neuropeptides in the genomes of parasitic flatworms using a novel comparative approach

2016/07/04 by Uriel Koziol, Miguel Koziol, Matías Preza +3 · 59 citations
Agricultural and Biological Sciences · Biochemistry, Genetics and Molecular Biology · Neuroscience · #Aquatic life and conservation #Biochemistry #Biology #Caenorhabditis #Caenorhabditis elegans #Drosophila melanogaster #Flatworm #Gene #Genetics #Genome #Hormone #Neurobiology and Insect Physiology Research #Neuropeptide #Neuropeptide Y receptor #Planarian #Prohormone #Prohormone convertase #Protein Hydrolysis and Bioactive Peptides #Zoology

paper · doi:10.1016/j.ijpara.2016.05.007

published in International Journal for Parasitology 46(11), 709-721 (Elsevier BV)

openalex publication_date 2016/07/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25

Cited by

• In silico analyses of neuropeptide-like protein (NLP) profiles in parasitic nematodes
• De novo transcriptome assembly and identification of G-Protein-Coupled-Receptors (GPCRs) in two species of monogenean parasites of fish
• System-wide mapping of peptide-GPCR interactions in C. elegans
• Profiling G protein-coupled receptors of Fasciola hepatica identifies orphan rhodopsins unique to phylum Platyhelminthes. [europepmc]
• Echinococcosis: Advances in the 21st Century. [europepmc]
• Broad tapeworms (Diphyllobothriidae), parasites of wildlife and humans: Recent progress and future challenges. [europepmc]
• Males, the Wrongly Neglected Partners of the Biologically Unprecedented Male-Female Interaction of Schistosomes. [europepmc]
• Towards deorphanizing G protein-coupled receptors of Schistosoma mansoni using the MALAR yeast two-hybrid system. [europepmc]
• Evolution and Comparative Physiology of Luqin-Type Neuropeptide Signaling. [europepmc]
• Peptidomics of Haemonchus contortus . [europepmc]
• Molecular topography of an entire nervous system. [europepmc]
• Identification of Putative Neuropeptides That Alter the Behaviour of Schistosoma mansoni Cercariae. [europepmc]
• Transcriptomic analysis supports a role for the nervous system in regulating growth and development of Fasciola hepatica juveniles. [europepmc]
• System-wide mapping of peptide-GPCR interactions in C. elegans. [europepmc]
• Rhodopsin orphan GPCR20 interacts with neuropeptides and directs growth, sexual differentiation, and egg production in female Schistosoma mansoni . [europepmc]
• Evolutionary conserved peptide and glycoprotein hormone-like neuroendocrine systems in C. elegans. [europepmc]
• Genome-wide transcriptome analysis of Echinococcus multilocularis larvae and germinative cell cultures reveals genes involved in parasite stem cell function. [europepmc]
• The muscle and neural architecture of Taenia crassiceps cysticerci revisited; implications on head-tail polarization of the larvae. [europepmc]
• A single-cell atlas of the miracidium larva of Schistosoma mansoni reveals cell types, developmental pathways, and tissue architecture. [europepmc]
• Peptidomic Identification of Behaviour-Modulating Putative Neuropeptides in Schistosoma mansoni Miracidia. [europepmc]
• System-wide mapping of neuropeptide-GPCR interactions in C. elegans [europepmc]