Dense granules: Are they key organelles to help understand the parasitophorous vacuole of all apicomplexa parasites?

2005/06/10 by Corinne Mercier, Koku D.Z. Adjogble, Walter Däubener +1 · 29 citations
Immunology and Microbiology · Medicine · #Toxoplasma gondii Research Studies #Parasitic Infections and Diagnostics #Herpesvirus Infections and Treatments

paper · doi:10.1016/j.ijpara.2005.03.011

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• Dense granule biogenesis, secretion, and function in Toxoplasma gondii
• Determining the protein repertoire of Cryptosporidium parvum sporozoites. [europepmc]
• Parasite stage-specific recognition of endogenous Toxoplasma gondii-derived CD8+ T cell epitopes. [europepmc]
• Toxoplasma gondii actively remodels the microtubule network in host cells. [europepmc]
• Toxoplasma gondii HLA-B*0702-restricted GRA7(20-28) peptide with adjuvants and a universal helper T cell epitope elicits CD8(+) T cells producing interferon-γ and reduces parasite burden in HLA-B*0702 mice. [europepmc]
• Proteomic analysis of fractionated Toxoplasma oocysts reveals clues to their environmental resistance. [europepmc]
• Epidemiology of and diagnostic strategies for toxoplasmosis. [europepmc]
• Evolution of apicomplexan secretory organelles. [europepmc]
• A HT/PEXEL motif in Toxoplasma dense granule proteins is a signal for protein cleavage but not export into the host cell. [europepmc]
• DNA prime and peptide boost immunization protocol encoding the Toxoplasma gondii GRA4 induces strong protective immunity in BALB/c mice. [europepmc]
• Phylogeny and virulence divergency analyses of Toxoplasma gondii isolates from China. [europepmc]
• Toxoplasma gondii ingests and digests host cytosolic proteins. [europepmc]
• Selective and strain-specific NFAT4 activation by the Toxoplasma gondii polymorphic dense granule protein GRA6. [europepmc]
• Asexual expansion of Toxoplasma gondii merozoites is distinct from tachyzoites and entails expression of non-overlapping gene families to attach, invade, and replicate within feline enterocytes. [europepmc]
• The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole. [europepmc]
• A Novel Secreted Protein, MYR1, Is Central to Toxoplasma's Manipulation of Host Cells. [europepmc]
• Phenotypes Associated with Knockouts of Eight Dense Granule Gene Loci (GRA2-9) in Virulent Toxoplasma gondii. [europepmc]
• Genomics of apicomplexan parasites. [europepmc]
• Dual role of the Toxoplasma gondii clathrin adaptor AP1 in the sorting of rhoptry and microneme proteins and in parasite division. [europepmc]
• Bioinformatics analysis of single and multi-hybrid epitopes of GRA-1, GRA-4, GRA-6 and GRA-7 proteins to improve DNA vaccine design against Toxoplasma gondii . [europepmc]
• Hardly Vacuous: The Parasitophorous Vacuolar Membrane of Malaria Parasites. [europepmc]
• Proximity biotinylation reveals novel secreted dense granule proteins of Toxoplasma gondii bradyzoites. [europepmc]
• From Signaling Pathways to Distinct Immune Responses: Key Factors for Establishing or Combating Neospora caninum Infection in Different Susceptible Hosts. [europepmc]
• Actin and an unconventional myosin motor, TgMyoF, control the organization and dynamics of the endomembrane network in Toxoplasma gondii. [europepmc]
• Dense granule biogenesis, secretion, and function in Toxoplasma gondii. [europepmc]
• Dense Granule Protein GRA64 Interacts with Host Cell ESCRT Proteins during Toxoplasma gondii Infection. [europepmc]