2026/07/27 by Xiujuan Gai, Shiqi Huang, Jinru Ye +7
paper · doi:10.1002/ijc.70631
ABSTRACT This study aimed to investigate whether hippocampal avoidance (D 40 40 40 ≤ 15 Gy. The incidence of anxiety was 0% (0/37) at the end of radiotherapy, which was lower than the 30.8% observed in the historical control group with hippocampal D 40 > 15 Gy ( p = 0.001). At 3 months post‐radiotherapy, no patients developed anxiety (0/34, 0%), and the incidence was 3.0% (1/33) at 6 months. The median MMSE score remained 29 from pre‐radiotherapy to the end of radiotherapy, and no significant decline in MMSE scores was observed at 3‐and 6‐month post‐radiotherapy compared with pre‐radiotherapy levels. Dosimetric evaluation confirmed acceptable target coverage, conformity, and homogeneity index. Collectively, hippocampal avoidance with bilateral D 40