2016/01/01 by Jasmien Roosenboom, Greet Hens, Brooke C. Mattern +2 · 2 citations
Biochemistry, Genetics and Molecular Biology · #dental development and anomalies #Cleft Lip and Palate Research #Craniofacial Disorders and Treatments
paper · pdf · doi:10.1155/2016/3054578
openalex publication_date 2016/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/27
The craniofacial complex is the billboard of sorts containing information about sex, health, ancestry, kinship, genes, and environment. A thorough knowledge of the genes underlying craniofacial morphology is fundamental to understanding craniofacial biology and evolution. These genes can also provide an important foundation for practical efforts like predicting faces from DNA and phenotype-based facial diagnostics. In this work, we focus on the various sources of knowledge regarding the genes that affect patterns of craniofacial development. Although tremendous successes recently have been made using these sources in both methodology and biology, many challenges remain. Primary among these are precise phenotyping techniques and efficient modeling methods.