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In Vitro Selection Identifies Staphylococcus aureus Genes Influencing Biofilm Formation

2023/02/27 by Dustin R. Long, Kelsi Penewit, Hsin‐Yu Lo +9 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Bacterial biofilms and quorum sensing #Antimicrobial Resistance in Staphylococcus

paper · doi:10.1128/iai.00538-22

Abstract

Staphylococcus aureus generates biofilms during many chronic human infections, which contributes to its growth and persistence in the host. Multiple genes and pathways necessary for S. aureus biofilm production have been identified, but knowledge is incomplete, and little is known about spontaneous mutations that increase biofilm formation as infection progresses.

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