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Single-molecule device prototypes for protein-based nanoelectronics: Negative differential resistance and current rectification in oligopeptides

2007/08/31 by David Cardamone, David M. Cardamone, George Kirczenow · 2 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Materials Science · Physics and Astronomy · #Advanced biosensing and bioanalysis techniques #Molecular Junctions and Nanostructures #Quantum Dots Synthesis And Properties #cond-mat.mes-hall

paper · pdf · doi:10.1103/physrevb.77.165403

published as Physical Review B, Volume 77, 165403 (2008) · 8 pages, 6 figures, 1 table. v2: new discussion of conductance as a function of molecular stretching, including new Fig. 3; expanded discussion of solution of the electrostatics problem; minor correction to Fig. 4 (was old Fig. 3); and minor clarifications throughout

arxiv created 2008/01/06 · openalex publication_date 2008/04/02 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/28

Abstract

Using ab initio and semiempirical techniques, we investigate electrical conduction through individual oligopeptide molecules thiol bonded between gold nanocontacts. Our theory explains these molecules' experimentally observed current-voltage characteristics, including both the magnitude and rectification of the current, and uses no adjustable parameters. We identify the mechanism of the observed current rectification, and predict that it will result in negative differential resistance at moderate biases. Our findings open the way to the realization of protein-based nanoelectronic devices.

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