Organotrifluoroborates: Protected Boronic Acids That Expand the Versatility of the Suzuki Coupling Reaction

2007/01/26 by Gary A. Molander, Noel M. Ellis · 7 citations
Chemistry · #Catalytic Cross-Coupling Reactions #Organoboron and organosilicon chemistry #Sulfur-Based Synthesis Techniques

paper · doi:10.1021/ar050199q

openalex publication_date 2007/01/26 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

Organotrifluoroborates represent an alternative to boronic acids, boronate esters, and organoboranes for use in Suzuki-Miyaura and other transition-metal-catalyzed cross-coupling reactions. The trifluoroborate moiety is stable toward numerous reagents that are often problematic for other boron species. Consequently, remote functional groups within the organotrifluoroborates can be manipulated, while retaining the valuable carbon-boron bond.

Citations

• The S tille Reaction

Cited by

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• The Slow‐Release Strategy in Suzuki–Miyaura Coupling
• Structure, Properties, and Preparation of Boronic Acid Derivatives
• How easy are the syntheses of allenes?
• Large-Scale Applications of Transition Metal-Catalyzed Couplings for the Synthesis of Pharmaceuticals
• Advances in Transition Metal (Pd,Ni,Fe)-Catalyzed Cross-Coupling Reactions Using Alkyl-organometallics as Reaction Partners
• Protodeboronation [wikipedia]