2008/02/08 by Massimo Bernaschi, Simone Melchionna, Sauro Succi +2
Biochemistry, Genetics and Molecular Biology · Engineering · Physics and Astronomy · #Lipid Membrane Structure and Behavior #Microfluidic and Capillary Electrophoresis Applications #Nanopore and Nanochannel Transport Studies #physics.bio-ph #physics.comp-ph
paper · pdf · doi:10.1021/nl073251f
6 pages, 5 figures, to appear in Nano Letters
arxiv created 2008/02/08 · openalex publication_date 2008/02/27 · arxiv updated 2009/12/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/28
We present a detailed description of biopolymer translocation through a nanopore in the presence of a solvent using an innovative multiscale methodology that treats the biopolymer at the microscopic scale as combined with a self-consistent mesoscopic description for the solvent fluid dynamics. We report evidence for quantized current blockade depending on the folding configuration and offer detailed information on the role of hydrodynamic correlations in speeding up the translocation process.