Highly efficient Grignard-type imine additions via C–H activation in water and under solvent-free conditions

2002/01/15 by Chao‐Jun Li, Chunmei Wei · 3 citations
Chemistry · #Asymmetric Hydrogenation and Catalysis #Catalytic C–H Functionalization Methods #Synthesis and Catalytic Reactions

paper · doi:10.1039/b108851n

openalex publication_date 2002/01/15 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/25

Abstract

A highly effective Cu-Ru catalyzed addition of terminal alkynes to imines via C-H activation has been achieved in water or under solvent-free conditions.

Cited by

• Redox‐Neutral Copper(II) Carboxylate Catalyzed α‐Alkynylation of Amines
• The Copper‐Catalyzed Decarboxylative Coupling of the sp3‐Hybridized Carbon Atoms of α‐Amino Acids
• A3 coupling reaction [wikipedia]