1970/03/19 by Louis M. Sherwood, Edith E. Parris, George F. Cahill · 4 citations
Medicine · Biochemistry, Genetics and Molecular Biology · #Diet and metabolism studies #Muscle metabolism and nutrition #Nutritional Studies and Diet
paper · doi:10.1056/nejm197003192821209
openalex publication_date 1970/03/19 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/31
ALTHOUGH it has been known for over a century that fat is the principal storage form of energy, only in the past two decades have the physiologic mechanisms for its deposition and mobilization been partially clarified. Benedict,1 in his classic study on Mr. L., a normal man who over 50 years ago fasted experimentally for 30 days, noted that fat provided more than 75 per cent of the calories utilized after the first few days of food deprivation. He also observed a progressive decrease in daily urinary nitrogen excretion that suggested an increasing conservation of body protein. In this review . . .