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Force-velocity relations of a two-state crossbridge model for molecular motors

1997/08/31 by Andrej Vilfan, Erwin Frey, Franz Schwabl · 2 citations
Physics and Astronomy · #Force Microscopy Techniques and Applications #Mechanical and Optical Resonators #cond-mat.soft #cond-mat.stat-mech #stochastic dynamics and bifurcation

paper · pdf · doi:10.1209/epl/i1999-00160-3

published as Europhys. Lett, 45, 283 (1999) · 5 pages, 4 figures, REVTeX; thoroughly revised version; also available at http://www.physik.tu-muenchen.de/~frey/

arxiv created 1998/06/08 · openalex publication_date 1999/02/01 · arxiv updated 2009/11/30 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/30

Abstract

We discuss the force-velocity relations obtained in a two-state crossbridge model for molecular motors. They can be calculated analytically in two limiting cases: for a large number and for one pair of motors. The effect of the strain-dependent detachment rate on the motor characteristics is studied. It can lead to linear, myosin-like, kinesin-like and anomalous curves. In particular, we specify the conditions under which oscillatory behavior may be found.

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