Diversity and Dynamics of Dendritic Signaling

2000/10/27 by Michael Häusser, Nelson Spruston, Greg J. Stuart · 6 citations
Neuroscience · #Neural dynamics and brain function #Photoreceptor and optogenetics research #Neuroscience and Neuropharmacology Research

paper · doi:10.1126/science.290.5492.739

openalex publication_date 2000/10/27 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/31

Abstract

Communication between neurons in the brain occurs primarily through synapses made onto elaborate treelike structures called dendrites. New electrical and optical recording techniques have led to tremendous advances in our understanding of how dendrites contribute to neuronal computation in the mammalian brain. The varied morphology and electrical and chemical properties of dendrites enable a spectrum of local and long-range signaling, defining the input-output relationship of neurons and the rules for induction of synaptic plasticity. In this way, diversity in dendritic signaling allows individual neurons to carry out specialized functions within their respective networks.

Citations

• Spatial profile of dendritic calcium transients evoked by action potentials in rat neocortical pyramidal neurones.
• The NEURON Simulation Environment
• Calcium action potentials restricted to distal apical dendrites of rat neocortical pyramidal neurons

Cited by

• Morphology of Fly Larval Class IV Dendrites Accords with a Random Branching and Contact Based Branch Deletion Model
• Neuromodulation of Na+ channels: An unexpected form of cellular platicity
• SINBAD: A neocortical mechanism for discovering environmental variables and regularities hidden in sensory input
• Arithmetic of Subthreshold Synaptic Summation in a Model CA1 Pyramidal Cell
• Impact of Active Dendrites and Structural Plasticity on the Memory Capacity of Neural Tissue
• Dendritic spike [wikipedia]