2012/01/01 by Isabelle Thomé, Anne Nijs, Carsten Bolm · 3 citations
Chemistry · #Asymmetric Hydrogenation and Catalysis #Catalytic Cross-Coupling Reactions #Catalytic C–H Functionalization Methods
paper · doi:10.1039/c2cs15249e
openalex publication_date 2012/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/15
Metal-catalysed transformations are a powerful tool in organic chemistry and the enormous progress, which has been made in the last few decades, was one more time honoured by the Nobel Prize in Chemistry in 2010. Many metal-containing compounds have been applied in carbon-carbon and carbon-heteroatom bond formations. However, not every component originally claimed as catalyst turned out to be the active ingredient in the end. Sometimes trace metal impurities were the actual catalytic species. In this tutorial review, we will highlight recent findings in transition metal-catalysed cross-coupling reactions and detail several reports from the past, which illustrate that "trace metal catalysis" is not a newly discovered phenomenon.