2005/05/31 by Jaime E. Santos, Jaime E Santos, Thomas Franosch +2
Biochemistry, Genetics and Molecular Biology · Medicine · Physics and Astronomy · #ATP Synthase and ATPases Research #Cardiomyopathy and Myosin Studies #Microtubule and mitosis dynamics #cond-mat.other #cond-mat.stat-mech #q-bio.OT #q-bio.SC
paper · pdf · doi:10.1088/1478-3975/2/3/008
published as Phys. Biol. 2, 207-222 (2005)
openalex publication_date 2005/10/13 · arxiv created 2005/11/13 · arxiv updated 2009/12/01 · openalex created_date 2016/06/24 · openalex updated_date 2026/07/30
We present a systematic method of analysis of experiments performed with single motor proteins. The use of such a method should allow a more detailed description of the motor's chemical cycle through the precise fitting of the experimental data. We model the dynamics of a processive or rotary molecular motor using a renewal process, in line with the work initiated by Svoboda, Mitra and Block. We apply a functional technique to compute different types of multiple-time correlation function of the renewal process, which have applications to bead-assay experiments performed both with processive molecular motors, such as myosin V and kinesin, and rotary motors, such as F1-ATPase.