2007/10/17 by Carlos F. Barbas · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Asymmetric Synthesis and Catalysis #Chemical Synthesis and Analysis #Chemical synthesis and alkaloids
paper · doi:10.1002/anie.200702210
openalex publication_date 2007/10/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/16
One enigma leads in three directions: The Hajos–Wiechert reaction presented an enigma that went unsolved for three decades. With the unravelling of this enigma, organocatalysis plays a major role in the development of efficient catalytic asymmetric methodologies. The mechanisms of organocatalysis also shed light on the origin of homochirality essential for life and provide clues to yet-to-be-discovered biosynthetic mechanisms at work in living organisms today.