2000/01/01 by Michael Frohn, Yian Shi · 181 citations
Chemistry · Materials Science · #Catalysis #Chemistry #Combinatorial chemistry #Enantioselective synthesis #Ketone #Organic Chemistry Cycloaddition Reactions #Organic chemistry #Oxidizing agent #Polyoxometalates: Synthesis and Applications #Reactivity (psychology) #Selectivity #Synthesis and Catalytic Reactions
paper · doi:10.1055/s-2000-8715
published in Synthesis 2000(14), 1979-2000 (Thieme Medical Publishers (Germany))
openalex publication_date 2000/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04
All articles of this category Dioxiranes are remarkably versatile oxidizing agents that show encouraging potential for asymmetric synthesis, particularly asymmetric epoxidation of unfunctionalized olefins. This review outlines the recent development in this area. Discussions are focused on the structural requirements of the chiral ketone catalysts, how structural changes effect the reactivity and selectivity of the catalyst, reaction conditions, and transition states. asymmetric epoxidation - chiral dioxirane - chiral ketone - epoxide - hydrogen peroxide - oxone - potassium peroxymonosulfate