A selective PIKfyve inhibitor blocks PtdIns(3,5)P2 production and disrupts endomembrane transport and retroviral budding

2008/01/11 by Harold B J Jefferies, Harold B.J. Jefferies, Frank T Cooke +12 · 5 citations
Biochemistry, Genetics and Molecular Biology · Medicine · #Autophagy in Disease and Therapy #Cellular transport and secretion #Genetics and Neurodevelopmental Disorders

paper · doi:10.1038/sj.embor.7401155

crossref issued 2008/01/11 · crossref published 2008/01/11 · crossref published-online 2008/01/11 · openalex publication_date 2008/01/11 · crossref created 2008/01/11 · crossref published-print 2008/02/01 · openalex created_date 2016/06/24 · crossref deposited 2026/05/18 · crossref indexed 2026/07/01 · openalex updated_date 2026/07/23

Citations

• Phosphatidylinositol 3,5-bisphosphate: metabolism and cellular functions
• The mammalian phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) regulates endosome-to-TGN retrograde transport

Cited by

• The Phosphoinositide Kinase PIKfyve Is Vital in Early Embryonic Development
• PIKfyve-ArPIKfyve-Sac3 Core Complex
• Kinesin Adapter JLP Links PIKfyve to Microtubule-based Endosome-to-Trans-Golgi Network Traffic of Furin
• ArPIKfyve Homomeric and Heteromeric Interactions Scaffold PIKfyve and Sac3 in a Complex to Promote PIKfyve Activity and Functionality
• Phosphatidylinositol 3,5-bisphosphate [wikipedia]