1993/05/01 by Gregory C. Fu, Robert H. Grubbs · 3 citations
Chemistry · #Chemistry #Citation #Computer science #Icon #Information retrieval #Metathesis #Olefin metathesis #Organic chemistry #Social media #Synthetic Organic Chemistry Methods #World Wide Web
paper · doi:10.1021/ja00062a066
openalex publication_date 1993/05/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/11
The development of efficient methods for constructing carbocycles continues to be an important goal of synthetic organic chemistry. One extremely useful approach to the formation of unsaturated carbocycles is the intramolecular dicarbonyl coupling reaction (eq 1). Oftentimes, the substrate employed in this process is generated by oxidation of a diene or of an olefinic ketone. In this communication, we report that transition-metal alkylidenes effect the direct synthesis of unsaturated carbocycles from either of these precursors (eqs 2 and 3).