2004/07/28 by Michael T. Crimmins, Brandon H. Brown · 2 citations
Chemistry · Environmental Science · #Synthetic Organic Chemistry Methods #Asymmetric Synthesis and Catalysis #Marine Toxins and Detection Methods
paper · doi:10.1021/ja046574b
openalex publication_date 2004/07/28 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
The enantioselective synthesis of the eunicellin ophirin B has been completed. A ring-closing metathesis provides efficient access to the oxonene ring, and a highly diastereoselective intramolecular Diels-Alder reaction results in the formation of the hydrobenzofuran portion of the molecule.