2007/02/23 by Jiří Pospíšil, István E. Markó · 1 citation
Biochemistry, Genetics and Molecular Biology · Chemistry · #Marine Sponges and Natural Products #Synthetic Organic Chemistry Methods #Chemical Synthesis and Reactions
paper · doi:10.1021/ja0691728
openalex publication_date 2007/02/23 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/02
A short and convergent synthesis of jerangolid D is described. As key steps, a Blaise reaction is employed to construct the lactone ring, a diastereoselective multicomponent Sakurai condensation leads to the dihydropyran ring, and the skipped diene is assembled using a modified Julia olefination.