2010/10/14 by D. Bradley G. Williams, Michelle Lawton · 5 citations
Environmental Science · Chemistry · #Chemistry and Chemical Engineering #Various Chemistry Research Topics #History and advancements in chemistry
paper · doi:10.1021/jo101589h
openalex publication_date 2010/10/14 · openalex created_date 2025/10/10 · openalex updated_date 2026/07/31
Various commonly used organic solvents were dried with several different drying agents. A glovebox-bound coulometric Karl Fischer apparatus with a two-compartment measuring cell was used to determine the efficiency of the drying process. Recommendations are made relating to optimum drying agents/conditions that can be used to rapidly and reliably generate solvents with low residual water content by means of commonly available materials found in most synthesis laboratories. The practical method provides for safer handling and drying of solvents than methods calling for the use of reactive metals, metal hydrides, or solvent distillation.