1969/08/01 by Esther Fujiwara, Matthias Brand, Lutz Kracht +7 · 2 citations
Medicine · Neuroscience · Psychology · #Amnesia #Anterograde amnesia #Autobiographical memory #Cognition #Cognitive psychology #Dementia and Cognitive Impairment Research #Developmental psychology #Epilepsy research and treatment #Episodic memory #Executive functions #Frontal lobe #Memory and Neural Mechanisms #Neuropsychology #Neuroscience #Psychology #Retrograde amnesia #Schizophrenia research and treatment #Social cognition
paper · doi:10.1016/j.cortex.2005.09.001
openalex publication_date 2007/12/06 · openalex created_date 2016/06/24 · openalex updated_date 2026/06/19
Functional retrograde amnesia (RA) is a rare pathology and has been rarely studied in detail across different patients. We extensively examined five functional RA patients and compared their neuropsychological profile including anterograde and retrograde memory performance, executive functions, emotional processing, and formally assessed psychiatric symptoms. Across patients, neuropsychological deficits beyond RA were most consistently seen in executive functions and attention suggesting that these dysfunctions contribute to the remote memory deficit. In a majority of the patients, problems in social cognition and emotional behaviour were reflected in Theory of Mind deficits and accompanying psychiatric symptoms. Aberrances in a measure of social desirability were detected, pointing to repressive tendencies in three out of the five patients. Future studies of functional RA patients may investigate more specifically which frontal-lobe associated (dys-) functions contribute to the memory retrieval deficit. Moreover, studying more closely the interaction between social cognition, repressive personality style and memory inhibition in this disease seems worthwhile pursuing.