1995/04/01 by Ned A. Porter, Sarah E. Caldwell, Karen A. Mills · 5 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · Medicine · #Antioxidant Activity and Oxidative Stress #Coenzyme Q10 studies and effects #Free Radicals and Antioxidants
paper · doi:10.1007/bf02536034
crossref issued 1995/04/01 · crossref published 1995/04/01 · crossref published-online 1995/04/01 · crossref published-print 1995/04/01 · openalex publication_date 1995/04/01 · crossref created 2006/11/29 · openalex created_date 2025/10/10 · crossref deposited 2025/10/20 · crossref indexed 2026/07/31 · openalex updated_date 2026/08/01
Abstract The primary producs formed from the autoxidation of lipids can be understood based upon a mechanism that involves five different reaction types. These reactions are: reaction of a carbon radical and molecular oxygen, atom transfer of a hydrogen from substrate to the chain carrying peroxyl, fragmentation of the chain carrying peroxyl to give oxygen and a carbon radical, rearrangement of the peroxyl, and cyclization of the peroxyl. The mechanisms of these primary reaction steps has been the focus of extensive research over the past fifty years, and the current level of understanding of these transformations is the subject of this review.