Analysis of the reactions used for the preparation of drug candidate molecules

2006/01/01 by John Carey, David Laffan, Colin Thomson +1 · 7 citations
Biochemistry, Genetics and Molecular Biology · Engineering · Environmental Science · #Chemistry and Chemical Engineering #Enzyme Catalysis and Immobilization #Innovative Microfluidic and Catalytic Techniques Innovation

paper · doi:10.1039/b602413k

openalex publication_date 2006/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04

Abstract

The purpose of this perspective is to indicate the range of chemistries used in the manufacture of drug candidate molecules and to highlight certain gaps in current technologies. To do this a survey was carried out of chemical syntheses within the Process Chemistry R&D departments of GlaxoSmithKline, AstraZeneca and Pfizer.

Citations

• Enantiospecific synthesis of SB 214857, a potent, orally active, nonpeptide fibrinogen receptor antagonist

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