2020/07/22 by Valeria Scaglioni, Enrique R. Soriano · 1 voice · 1 citation
Medicine · #COVID-19 Clinical Research Studies #Long-Term Effects of COVID-19 #SARS-CoV-2 and COVID-19 Research
paper · doi:10.1111/sji.12944
openalex publication_date 2020/07/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/05/21
Right now the world is going through an unprecedented pandemic caused by a novel coronavirus. Recent papers pointed out the fatal outcome in most of the severe cases, in which a cytokine storm has been proven to be the cause of a systemic shock, acute respiratory syndrome, multiorgan failure and consequently death. Several explanations have been proposed trying to explain the pathophysiology of the cytokine storm, but viral proteins with a possible superantigen activity as a cause of immune dysregulation have not been addressed. If this hypothesis is proven, a different treatment approach might change the outcome in severe cases.