Mapping the structure–activity landscape of non-canonical peptides with MAP4 fingerprinting

2023/01/01 by Edgar López‐López, Oscar Robles, Fabien Plisson +1 · 1 voice
Biochemistry, Genetics and Molecular Biology · Immunology and Microbiology · #Antimicrobial Peptides and Activities #Chemical Synthesis and Analysis #RNA and protein synthesis mechanisms

paper · pdf · doi:10.1039/d3dd00098b

openalex publication_date 2023/01/01 · openalex created_date 2025/10/10 · openalex updated_date 2026/06/27

Abstract

Peptide structure–activity/property relationship (P-SA/PR) studies focus on understanding how the structural variations of peptides influence their biological activities and other functional properties.

Citations

• Effects of net charge and the number of positively charged residues on the biological activity of amphipathic α‐helical cationic antimicrobial peptides
• Sustainability Challenges in Peptide Synthesis and Purification: From R&D to Production
• Machine learning-guided discovery and design of non-hemolytic peptides
• Trends in peptide drug discovery
• Biomimetic peptide self-assembly for functional materials
• Natural product drug discovery in the artificial intelligence era

Discussions

• Excellent collaboration with @difacquim @EdgarLpezLpez10 & @OscarRoblz on "mapping the structure-activity landscape of peptides with non-canonical residues" #peptide2drug #MRSA #dataviz doi.org/10.10 [bsky, 0 points, 0 comments]