Construction of a genetic toggle switch in Escherichia coli

2000/01/01 by Timothy S. Gardner, Charles R. Cantor, James J. Collins · 1 voice · 32 citations
Biochemistry, Genetics and Molecular Biology · Physics and Astronomy · #Evolution and Genetic Dynamics #Gene Regulatory Network Analysis #Origins and Evolution of Life

paper · doi:10.1038/35002131

crossref issued 2000/01/01 · crossref published 2000/01/01 · crossref published-print 2000/01/01 · openalex publication_date 2000/01/01 · crossref created 2002/07/26 · crossref deposited 2023/05/17 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04 · crossref indexed 2026/08/04

Citations

• General Conclusions: Teleonomic Mechanisms in Cellular Metabolism, Growth, and Differentiation

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Discussions

• Going back to methods to generate heterogeneity - I always thought this paper by JJ Collins was overlooked (even though in Nature) - you just need the right interacting regulatory systems to generate [bsky, 0 points, 1 comments]