2023/10/23 by Romain Derelle, John A. Lees, Jody Phelan +3 · 1 voice
Biochemistry, Genetics and Molecular Biology · Medicine · #Genomics and Phylogenetic Studies #Mycobacterium research and diagnosis #Tuberculosis Research and Epidemiology
paper · pdf · doi:10.1093/bioinformatics/btad648
openalex publication_date 2023/10/23 · openalex created_date 2023/10/24 · openalex updated_date 2026/07/02
SUMMARY: Fastlin is a bioinformatics tool designed for rapid Mycobacterium tuberculosis complex (MTBC) lineage typing. It utilizes an ultra-fast alignment-free approach to detect previously identified barcode single nucleotide polymorphisms associated with specific MTBC lineages. In a comprehensive benchmarking against existing tools, fastlin demonstrated high accuracy and significantly faster running times. AVAILABILITY AND IMPLEMENTATION: fastlin is freely available at https://github.com/rderelle/fastlin and can easily be installed using Conda.