Powder diet exacerbates oropharyngeal candidiasis in a mouse model

2024/02/06 by Roberto Vázquez-Muñoz, Angela Thompson, Takanori Sobue +1 · 1 voice
Medicine · Dentistry · #Antifungal resistance and susceptibility #Oral microbiology and periodontitis research #Fungal Infections and Studies

paper · pdf · doi:10.1128/aem.01713-23

openalex publication_date 2024/02/06 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01

Abstract

infection in this model. Future research should investigate this relationship further to broaden our understanding of the underlying mechanisms, potentially leading to novel prevention strategies and improved disease management.IMPORTANCEOropharyngeal candidiasis (OPC) is a multifactorial disease and a significant health concern. We found that the physical form of the diet plays a critical role in the severity and progression of OPC. We developed a modified cortisone OPC murine model that facilitates studies investigating pathogenesis and recovery processes.

Citations

• A neglected epidemic: fungal infections in HIV/AIDS

Discussions

• #AEMJournal In Press | Vazquez-Munoz and team share how something as simple as switching to a powder diet instead of pellets can aggravate oropharyngeal candidiasis in a mouse model doi.org/10.1128/ae [bsky, 0 points, 0 comments]