Ligand and Target Discovery by Fragment-Based Screening in Human Cells

2017/01/01 by Christopher G. Parker, Andrea Galmozzi, Yujia Wang +11 · 1 voice · 2 citations
Biochemistry, Genetics and Molecular Biology · Chemistry · #Chemical Synthesis and Analysis #Click Chemistry and Applications #Ubiquitin and proteasome pathways

paper · doi:10.1016/j.cell.2016.12.029

crossref issued 2017/01/01 · crossref published 2017/01/01 · crossref published-print 2017/01/01 · openalex publication_date 2017/01/01 · crossref created 2017/01/19 · crossref deposited 2018/09/04 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01 · crossref indexed 2026/08/04

Citations

• Computational Methods in Drug Discovery

Cited by

• Ligand-binding pockets in RNA and where to find them
• A Chemical Biology View of Bioactive Small Molecules and a Binder‐Based Approach to Connect Biology to Precision Medicines

Discussions

• Great to see this amazing study and rich data resource, which is a highly valuable extension of the pioneering work done by Chris Parker in the group of Ben Cravatt. doi.org/10.1016/j.ce... [bsky, 0 points, 0 comments]