Sex differences in immune responses

2016/08/22 by Sabra L. Klein, Katie L. Flanagan · 1 voice · 20 citations
Immunology and Microbiology · Medicine · #Immune Cell Function and Interaction #Reproductive System and Pregnancy #Sex and Gender in Healthcare

paper · doi:10.1038/nri.2016.90

crossref issued 2016/08/22 · crossref published 2016/08/22 · crossref published-online 2016/08/22 · openalex publication_date 2016/08/22 · crossref created 2016/08/22 · crossref published-print 2016/10/01 · crossref deposited 2024/12/11 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/04 · crossref indexed 2026/08/04

Citations

• Estrogen receptors regulate innate immune cells and signaling pathways
• Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination

Cited by

• Epigenetic remodeling by sex hormone receptors and implications for gender affirming hormone therapy
• Developmental mechanisms of sex differences: from cells to organisms
• Increased risk of asthma in female night shift workers
• Challenges with embedding an integrated sex and gender perspective into pain research: Recommendations and opportunities
• More than just a pretty face? The relationship between immune function and perceived facial attractiveness
• The interaction of genetic sex and prenatal alcohol exposure on health across the lifespan
• Role of inflammation in depressive and anxiety disorders, affect, and cognition: genetic and non-genetic findings in the lifelines cohort study
• Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease
• Age and Sex Effects on Blood Retrotransposable Element Expression Levels: Findings From the Population‐Based Rhineland Study
• The Role of Immune Factors in Shaping Fetal Neurodevelopment
• Progress and Pitfalls in the Quest for Effective SARS-CoV-2 (COVID-19) Vaccines
• Sexual Dimorphisms in Innate Immunity and Responses to Infection in Drosophila melanogaster
• Type I Interferons in COVID-19 Pathogenesis
• Kinetics of rabies-neutralising antibodies in non-human primates after the injection of adjuvanted and inactivated rabies vaccine
• Sexual dimorphism in immunity across animals: a meta‐analysis
• Increased infection risk in patients on preventive CGRP-targeting therapies– a meta-analysis and clinical effect assessment
• Immunization Strategies Producing a Humoral IgG Immune Response against Devil Facial Tumor Disease in the Majority of Tasmanian Devils Destined for Wild Release
• Exploring craniofacial fluctuating asymmetry in a South African sample
• Gut microbiota and immune response under chronic social stress in an LPS-induced inflammatory model
• Biological Sex and Body Mass Index Influence the Longitudinal Evolution of Adolescent and Young Adult Magnetic Resonance Imaging-Visible Perivascular Spaces

Discussions

• #ShareAFactNoOneAskedFor Females are nearly twice as responsive to the influenza vaccine as males. When a female mouse is given a half dose and the male, a full dose, they achieve comparable immunity. [bsky, 0 points, 0 comments]