2024/11/22 by John W. Frew, Annika Smith, Pablo Fernández‐Peñas +10 · 1 voice
Medicine · #Hidradenitis Suppurativa and Treatments #Colorectal and Anal Carcinomas #Microscopic Colitis
paper · pdf · doi:10.1111/ajd.14388
openalex publication_date 2024/11/22 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
Hidradenitis Suppurativa is a burdensome inflammatory skin disease with significant quality of life impact. These management guidelines were developed to direct appropriate clinical management in the Australasian context. A systematic review was used for the basis of the consensus guidelines. Thirteen clinical experts were involved in a modified Delphi consensus process to develop the guidelines and treatment algorithms. Overall management strategies include appropriate severity assessment of disease and comorbidities, multimodal therapy with systemic and local treatments, and evidence-based progression along the therapeutic ladder in the event of inadequate response. Sequential monotherapy with antibiotics and/or single agent therapy is discouraged and aggressive treatment of moderate to severe disease to capture the window of opportunity is highly emphasised. Specific considerations in the setting of disease comorbidities, pregnancy and breastfeeding are also addressed. Overall, the complex nature of HS requires a complex and multimodal therapeutic response with medical, physical and surgical therapies to achieve best patient outcomes.