2022/10/19 by Janet Y. Lee, Stephen M. Rosenthal · 1 voice · 1 citation
Medicine · Psychology · #LGBTQ Health, Identity, and Policy #Reproductive Health and Technologies #Sexuality, Behavior, and Technology
paper · pdf · doi:10.1146/annurev-med-043021-032007
openalex publication_date 2022/10/19 · openalex created_date 2025/10/10 · openalex updated_date 2026/08/01
Increasing numbers of transgender and gender-diverse (TGD) youth, from early puberty through late adolescence, are seeking medical services to bring their physical sex characteristics into alignment with their gender identity-their inner sense of self as male or female or elsewhere on the gender spectrum. Numerous studies, primarily of short- and medium-term duration (up to 6 years), demonstrate the clearly beneficial-even lifesaving-mental health impact of gender-affirming medical care in TGD youth. However, there are significant gaps in knowledge and challenges to such care. Long-term safety and efficacy studies are needed to optimize medical care for TGD youth.